JOHNSON COUNTY COMMUNITY COLLEGE
Department of Life Sciences
Human Pathophysiology "Online"
COURSE OUTLINE
DIVISION: Science, Health Care and Math
MOST RECENT DATE REVISED: Fall 2007
COURSE TITLE: Human Pathophysiology
CREDIT: 4
COURSE NUMBER: BIOL 227
CONTACT HOURS: Asynchronous CLASS LECTURE: 0 LAB: 0
COURSE TYPE: Transfer
COURSE DESCRIPTION:
This introduction to the physiology of disease covers common disorders of the body from the cellular to the systemic level. Topics include: causes, symptoms, diagnostic tests and treatments of disease. The Entire Material except for the midterm Exam and the final Exam will be delivered and received through the the World Wide Web (WWW). However the Instructor can also be reached by phone.
There will be weekly assignments for which students summarize there work and send it to the instructor for grading. Students will be informed of there grades. after a week of there submission to the work. Students can also join a live chat twice a week to discuss any of there concerns.
PREREQUISITE(S):
BIOL 140, Human Anatomy OR BIOL 144, Human Anatomy and Physiology AND BIOL 225, Human Physiology
REQUIRED TEXTBOOKS Burns, Mary V. Pathophysiology, A self-Instructional Program, Appleton & Lange. (ISBN 0-8385-8084-X) available in the college bookstore
:
SUPPLEMENTARY TEXTBOOKS: None
SUPPLIES: Computer and Internet access
COURSE OBJECTIVES:
Upon completion of this course, the student will be able to:
1. Describe the different components of the human body, including cells, tissues, fluid compartments, organ systems
2. List general abnormalities in these components that may lead to disease
3. Trace the development of medicine from its earliest practice to modern times, describing major contributions of specific civilizations and scientists.
4. Correctly relate the 12 causes of diseases to the disease.
5. Associate certain special diagnostic tests to the correct disease.
5. Relate to special disorders such as in pregnancy, newborn and psychiatry.
6. describe the principle of the body’s defense mechanisms
7. Discuss verbally or in writing of the causes of selected diseases and their interrelationships.
8. Describe the clinical manifestations of specific diseases.
9. Describe the major disease processes and selected modes of prevention and treatment.
10. Correctly relate specific disorders to a particular system and its functions. This includes the 11 basic systems of the body.
COURSE OUTLINE AND COMPETENCIES:
I. The Human Body
A. Tissue Types
1. List the major four types of tissues found in the human body
2. Explain the functions of each of these tissues
B. Cell Physiology
1. Explain the basic physiological processes that take place in the cells, such as metabolism, protein synthesis, and cell division
2. List the steps for each of the above processes
3. Give examples of abnormalities that may occur during the course of these processes and explain how these abnormalities may contribute to the development of certain diseases.
C. Body Fluids
1. List the different body fluid compartments and explain their relationship to each other
2. Explain how changes in any of compartment contribute to changes in the whole body
3. Give examples of diseases caused by such changes
D. Organ Systems
1. Identify the different organs and their relationship the systems of the body.
2. Explain how a single organ may have more than one function and how organ systems work together to express the synergistic nature of the human body
II. The History of Medicine
A. Describe the contributions of major civilizations throughout history to medicine, including Ancient Egyptians, Greeks, Romans, and Chinese contributions
B. Describe the major scientists who contributed to the development of medicine preceding the twentieth century
C. Describe the most recent major contributions to medicine, including molecular biology, genetic engineering, and the use of technology
III. Classifications of Disease
A. List the major categories of disease, including hereditary, congenital, traumatic, iatrogenic physical, chemical, infectious, inflammatory, vascular, metabolic, nutritional, psychologic, idiopathic, and tumors
B. Give example of specific disease for each of the above categories
C. Describe the physiological basis of each disease
D. Describe the methods of diagnosis and treatment of each disease
IV. Disease Processes
A. Disturbances of Blood Flow and Derangement of Body Fluids
1. Describe the forces involved in the normal fluid exchange between the different compartments of the body.
2. Describe the basic principles of edema and list the blood and fluid abnormalities that lead to edema.
3. List some blood and fluid disturbances, including hemorrhage, thrombosis, embolism, ischemia, and hypertension.
4. list the pathophysiological causes of the above disturbances and explain their effect on the normal function of the body, including dehydration, shock and acid-base balance.
B. Inflammation and Repair
1. Explain the general principles of inflammation and list the steps of its development.
2. Describe the cellular and humoral responses to injury.
3. Describe the systemic defense mechanisms, including fever, leukocytosis, and pain.
4. Describe the usual results and complications of inflammation and distinguish between acute and chronic inflammation.
5. List the normal steps of healing and repair.
6. Explain the principal steps of inflammation management
C. Immune Functions and Disorders
1. List the cells involved in immune response and describe their activities.
2. Describe the chemical nature of antibodies and explain the steps of their synthesis
3. Explain the phenomenon of antibody-antigen reaction and describe its contributions to the body's defense mechanism.
4. Explain the meaning of some terms related to the immune system and its disorders, including cytokines, immunity, hypersensitivity.
5. Describe the four types of hypersensitivity reactions, including anaphylaxis, cytotoxic, immune complex-mediated hypersensitivity, and cell-mediated reactions.
6. Explain the difference between inherited and acquired forms of immunodeficiency, and give specific examples for each form.
7. Explain the general principles of autoimmune disorders and give example of specific diseases classified under this category
D. Infectious Diseases
1. Describe the basic pathophysiology of microbial infection and disease, including bacterial, viral, fungal parasitic, and neoplasia infections.
2. Give examples and statistics of incidence for each of the above infections
3. Describe their method of their diagnosis and treatment.
E. Inherited Disease
1. Define the meaning of heredity and inherited disease.
2. Give examples of inherited diseases and list their causes
3. Describe the methods involved in the diagnosis and treatment of inherited diseases
V. Organs (Systems) and Their Diseases
A. List some diseases related to specific organs and/or systems, including circulation, respiration, digestion, liver and gall bladder, pancreas, kidney, reproduction organs, endocrine glands, blood and lymphatics, nervous system, musculoskeletal system
B. Explain the physiological disorders involved in developing these diseases
C. Describe the methods of diagnosis and treatment of the above diseases
METHOD OF EVALUATION:
Assignments 20% of grade
Midterm Exam 40% of grade
Final Exam 40% of grade
Both exams will be taken in the testing lab on Campus
CAVEATS: